Brain Atrophy Correlated with Early Alzheimer's, Test Scores

A new study examines atrophy in the brain, signs of early Alzheimer's, and test scores from the mini mental status exam, a 1970's questionnaire administered verbally by health practitioners to assess rough changes in mental fitness. Atrophy was detected via the work of Linda K. McEvoy, Ph.D., of the University of California San Diego, and colleagues with the Alzheimer's Disease Neuroimaging Initiative (ADNI), analyzing magnetic resonance images from 139 healthy controls, 84 patients with mild Alzheimer's disease and 175 patients with mild cognitive impairment (MCI), using volumetric segmentation and cortical surface reconstruction methods, then measured with the test scores.

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