3.16.2006

An Early Indicator of Alzheimer's Identified
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amyloid proteins

A University of Minnesota team has identified what could be the earliest indication of Alzheimer's, a discovery that may help to diagnose the disease and perhaps stop it progressing.

Researchers believe that some people show signs of memory loss years before they develop Alzheimer's. But they are not sure what causes these problems, or how they turn into full-blown dementia.

To find out, Karen Ashe at the University of Minnesota, Minneapolis, and her team studied a strain of mice that, like people, develop mild memory problems in middle age before getting more severe Alzheimer's symptoms. The suspicion is that renegade proteins, known as amyloids, accumulate and begin to cause issues...

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