Aricept Effective in New Study

Drug Appears Effective for Severe Alzheimer's Cases
03.23.06, 12:00 AM ET

THURSDAY, March 23 (CogLabs Newswire) -- Aricept, which is typically used to treat mild-to-moderate Alzheimer's disease, seems to reverse some cognitive and functional deterioration in patients with severe forms of the disease, Swedish researchers report.

The potential benefit of Aricept (donepezil) to treat Alzheimer's patients with severe dementia had not been studied until now. Some 20 percent of Alzheimer's patients suffer from severe dementia; as the disease progresses, they become less able to communicate, less mobile, and increasingly reliant on nursing care.

In the trial, a research team led by Dr. Bengt Winblad, director of the Karolinska Institute's neurology department, assigned 248 Alzheimer's patients living in nursing homes to receive donepezil or a placebo for six months...

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