9.28.2008

Scientist Leroy Hood Calls for Genome-Based Health
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Dr. Leroy Hood, former Bill Gates professor of Biomedical Sciences at Washington, and who runs the Institute for Systems Biology, is calling for a Genome-based approach to healthcare.

Rather than treating symptoms after they begin occurring, why not get an alert about possible issues and be proactive?

More knowledge about genes makes this possible.

Hood is also on the advisory board of Taiwan Genome Sciences, a company which has proposed an extensive partnership with us (Cognitive Labs) before.

Wired reports on the several components of Hood's vision...

Predictive


The vision
Using genome sequencing and blood tests, a doctor will be able to determine a patient's probability of developing certain diseases. The price of these tests is dropping and will soon be less than $1,000 — the same as a CT scan today.

The challenge
Physicians will have to be trained to use the technology ethically. Patients will have to make sense of new kinds of choices.

Preventive

The vision
Based on an individualized risk profile, you could start therapies in advance to cut the likelihood of illness. Drugs could be designed to blunt the desire to overeat, drink, or smoke. Average lifespan could be extended by 10 to 30 years.

The challenge
What qualifies as a disease? Will we have fewer football players if we quiet the genes that drive aggression?

Personalized

The vision
With billions of data points for every patient, drug therapies can be created to suit each genome. This would eliminate the trial-and-error approach doctors use today.

The challenge
Having your genome on Google could be a huge privacy risk. With so much information around, data security will become an important field in the health care industry.

Participatory

The vision
People will maintain their own health, not just by treating existing illnesses but by learning about their own predispositions.

The challenge
How to explain biomarkers to someone with little grasp of science? Hood proposes games that teach health concepts, and his Institute for Systems Biology is working with school districts to develop top-notch science curricula.

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